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• Activity deltas table
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Motif ID: RXR{A,B,G}.p2

Z-value: 0.855

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_-_139128777	3.616		DPP7	dipeptidyl-peptidase 7
chr22_+_18081968	1.697	NM_002688	SEPT5	septin 5
chr5_+_149845503	1.586		NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr22_+_18085990	1.544		SEPT5-GP1BB SEPT5	SEPT5-GP1BB read-through transcript septin 5
chr22_+_18085891	1.518		SEPT5	septin 5
chr1_-_47468029	1.416	NM_003189	TAL1	T-cell acute lymphocytic leukemia 1
chr2_+_113709553	1.362		LOC654433	hypothetical LOC654433
chr12_+_52105131	1.336		AMHR2	anti-Mullerian hormone receptor, type II
chr7_-_150283794	1.307	NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr4_+_134292630	1.255		PCDH10	protocadherin 10
chr6_+_43846372	1.074		VEGFA	vascular endothelial growth factor A
chr7_-_150305933	1.069	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_-_150306169	1.065		KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr17_+_44429748	1.032	NM_001160423 NM_006546	IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1
chr6_-_2916280	1.021		SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr9_-_139128979	0.943		DPP7	dipeptidyl-peptidase 7
chr10_-_17536181	0.941	NM_001004470	ST8SIA6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr19_+_18391211	0.926	NM_001009998 NM_032627	SSBP4	single stranded DNA binding protein 4
chr19_-_54350457	0.906	NM_002152	HRC	histidine rich calcium binding protein
chr6_+_43846735	0.864		VEGFA	vascular endothelial growth factor A
chr4_+_134293171	0.859		PCDH10	protocadherin 10
chr19_+_18391423	0.808
chr11_-_75595098	0.802	NM_004626	WNT11	wingless-type MMTV integration site family, member 11
chr19_+_16860807	0.801	NM_003950	F2RL3	coagulation factor II (thrombin) receptor-like 3
chr7_-_3049872	0.799	NM_032415	CARD11	caspase recruitment domain family, member 11
chr21_-_32879617	0.744	NM_144659	TCP10L	t-complex 10 (mouse)-like
chr19_-_55834895	0.730	NM_001160328 NM_001160329	SYT3	synaptotagmin III
chr16_-_87244896	0.722	NM_000101	CYBA	cytochrome b-245, alpha polypeptide
chr1_+_12149662	0.716		TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B
chr7_+_154720547	0.702		INSIG1	insulin induced gene 1
chr7_+_128219307	0.684	NM_022742	CCDC136	coiled-coil domain containing 136
chr9_-_139128983	0.674		DPP7	dipeptidyl-peptidase 7
chr17_-_24491521	0.670		MYO18A	myosin XVIIIA
chr17_+_78286687	0.653	NM_022158	FN3K	fructosamine 3 kinase
chr20_-_23014828	0.648	NM_012072	CD93	CD93 molecule
chr21_+_39099717	0.639	NM_005239	ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr9_-_130006309	0.634	NM_001131015 NM_012127	CIZ1	CDKN1A interacting zinc finger protein 1
chr4_-_10068055	0.634	NM_053042	ZNF518B	zinc finger protein 518B
chr19_-_772966	0.620		LPPR3	lipid phosphate phosphatase-related protein type 3
chr5_-_132141368	0.619	NM_001098813	SEPT8	septin 8
chr21_+_39099624	0.618		ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr11_+_47543463	0.611	NM_001143984 NM_175732	PTPMT1	protein tyrosine phosphatase, mitochondrial 1
chr9_+_102275310	0.609	NM_003692	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr19_-_772913	0.606	NM_024888	LPPR3	lipid phosphate phosphatase-related protein type 3
chr9_-_139128990	0.603		DPP7	dipeptidyl-peptidase 7
chr3_-_188339882	0.598	NM_052969	RPL39L	ribosomal protein L39-like
chr9_-_139128992	0.591		DPP7	dipeptidyl-peptidase 7
chr9_-_139128988	0.590		DPP7	dipeptidyl-peptidase 7
chr7_-_37454933	0.588	NM_014800	ELMO1	engulfment and cell motility 1
chr6_-_85529031	0.588		TBX18	T-box 18
chr11_+_65162114	0.587	NM_006747	SIPA1	signal-induced proliferation-associated 1
chr19_-_1125257	0.583		SBNO2	strawberry notch homolog 2 (Drosophila)
chr6_+_24602995	0.581		ALDH5A1	aldehyde dehydrogenase 5 family, member A1
chr6_-_167289659	0.573
chr19_-_50840446	0.556	NM_001193268	EML2	echinoderm microtubule associated protein like 2
chr1_+_14797764	0.554	NM_015209 NM_201628	KAZN	kazrin, periplakin interacting protein
chrX_-_153632990	0.554		GAB3	GRB2-associated binding protein 3
chr19_-_971995	0.550		C19orf6	chromosome 19 open reading frame 6
chr3_-_38666122	0.549	NM_000335 NM_001099404 NM_001099405 NM_198056 NM_001160160 NM_001160161	SCN5A	sodium channel, voltage-gated, type V, alpha subunit
chr6_-_2916786	0.545		SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr19_+_16860871	0.542		F2RL3	coagulation factor II (thrombin) receptor-like 3
chr15_-_73818013	0.540
chr19_+_18312365	0.538	NM_017712	FKBP8 PGPEP1	FK506 binding protein 8, 38kDa pyroglutamyl-peptidase I
chr20_-_34925483	0.536	NM_080627	KIAA0889	KIAA0889
chr19_+_4255590	0.533	NM_024333	FSD1	fibronectin type III and SPRY domain containing 1
chr11_-_76059435	0.533	NM_001128922	LRRC32	leucine rich repeat containing 32
chr1_-_1840564	0.531	NM_178545	TMEM52	transmembrane protein 52
chr17_+_34115383	0.524	NM_005937	MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr19_+_40824486	0.505	NM_014209	ETV2	ets variant 2
chr14_+_28306633	0.497		FOXG1	forkhead box G1
chr18_+_75261231	0.496	NM_172387 NM_172389	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr11_+_43920385	0.494	NM_001145033	C11orf96	chromosome 11 open reading frame 96
chr16_+_88305743	0.489		LOC100128881	hypothetical LOC100128881
chr1_-_152185764	0.485	NM_014856	DENND4B	DENN/MADD domain containing 4B
chr19_-_4509471	0.485	NM_032108	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr9_-_109291575	0.485		KLF4	Kruppel-like factor 4 (gut)
chr9_-_122679387	0.485	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr6_+_24603145	0.484	NM_001080 NM_170740	ALDH5A1	aldehyde dehydrogenase 5 family, member A1
chr9_-_122679283	0.483		PHF19	PHD finger protein 19
chr19_-_1125263	0.483	NM_014963	SBNO2	strawberry notch homolog 2 (Drosophila)
chr10_-_17536351	0.481		ST8SIA6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr19_-_972122	0.481	NM_001033026 NM_033420	C19orf6	chromosome 19 open reading frame 6
chr7_+_75864755	0.481	NM_007155	ZP3	zona pellucida glycoprotein 3 (sperm receptor)
chr11_-_86343859	0.477	NM_012193	FZD4	frizzled homolog 4 (Drosophila)
chr19_-_17349096	0.476	NM_031310	PLVAP	plasmalemma vesicle associated protein
chr8_+_77928372	0.475		ZFHX4	zinc finger homeobox 4
chr19_+_54226941	0.472	NM_033378	CGB1 CGB2	chorionic gonadotropin, beta polypeptide 1 chorionic gonadotropin, beta polypeptide 2
chr4_-_2336328	0.471	NM_001172659 NM_001172660	ZFYVE28	zinc finger, FYVE domain containing 28
chr16_+_29582065	0.471		SPN	sialophorin
chr19_+_13066956	0.466		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr3_+_161425946	0.466	NM_001168214	LOC401097	hypothetical protein LOC401097
chr17_-_53420473	0.463		VEZF1	vascular endothelial zinc finger 1
chr17_-_7106987	0.456	NM_001185023 NM_001307	CLDN7	claudin 7
chr19_+_3457264	0.456	NM_016263	FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)
chr5_+_168996816	0.455	NM_004946	DOCK2	dedicator of cytokinesis 2
chrX_+_44617346	0.455	NM_021140	KDM6A	lysine (K)-specific demethylase 6A
chr1_-_200396328	0.454		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr16_+_29582069	0.449	NM_003123	SPN	sialophorin
chr1_-_154665807	0.447	NM_006365	C1orf61	chromosome 1 open reading frame 61
chr19_+_7607976	0.446	NM_001127396 NM_006949	STXBP2	syntaxin binding protein 2
chr4_+_658250	0.446		MYL5	myosin, light chain 5, regulatory
chr16_+_162845	0.442	NM_000517	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr5_-_131591380	0.440	NM_001017974 NM_001142598 NM_001142599	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr22_+_29151651	0.439	NM_001003704 NM_016498	MTFP1	mitochondrial fission process 1
chr19_-_18409788	0.432	NM_001170939	ISYNA1	inositol-3-phosphate synthase 1
chr1_-_154727014	0.431		MEF2D	myocyte enhancer factor 2D
chr19_+_10404110	0.429	NM_001111309	PDE4A	phosphodiesterase 4A, cAMP-specific
chr19_-_4016467	0.428		ZBTB7A	zinc finger and BTB domain containing 7A
chr19_+_7608020	0.428		STXBP2	syntaxin binding protein 2
chrX_-_48929789	0.425		PRICKLE3	prickle homolog 3 (Drosophila)
chrX_-_70391127	0.423	NM_001171163 NM_005096	ZMYM3	zinc finger, MYM-type 3
chr11_+_46256130	0.421		CREB3L1	cAMP responsive element binding protein 3-like 1
chrX_-_135677022	0.420		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr19_+_1223475	0.419		CIRBP	cold inducible RNA binding protein
chr6_+_43846155	0.418		VEGFA	vascular endothelial growth factor A
chrX_+_117513899	0.418	NM_144658	DOCK11	dedicator of cytokinesis 11
chrX_-_138114100	0.415		FGF13	fibroblast growth factor 13
chr19_+_54723044	0.413		RCN3	reticulocalbin 3, EF-hand calcium binding domain
chr20_-_43972949	0.411		PLTP	phospholipid transfer protein
chr5_-_134762785	0.409		H2AFY	H2A histone family, member Y
chr20_+_48032918	0.409	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr22_+_21742364	0.407	NM_002073	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr5_-_134762791	0.404		H2AFY	H2A histone family, member Y
chr12_+_130979696	0.404	NM_001002020	PUS1	pseudouridylate synthase 1
chr19_+_7608010	0.404		STXBP2	syntaxin binding protein 2
chr17_-_59131210	0.401	NM_030576	LIMD2	LIM domain containing 2
chr5_-_134762814	0.396	NM_001040158 NM_138609 NM_138610	H2AFY	H2A histone family, member Y
chr17_+_16259573	0.395	NM_016113	TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr14_+_57835028	0.393		ARID4A	AT rich interactive domain 4A (RBP1-like)
chr3_+_161426322	0.393		LOC401097	hypothetical protein LOC401097
chr19_+_7608015	0.393		STXBP2	syntaxin binding protein 2
chrX_-_48929685	0.391	NM_006150	PRICKLE3	prickle homolog 3 (Drosophila)
chr4_-_129105733	0.390		MFSD8	major facilitator superfamily domain containing 8
chr19_-_7896974	0.390	NM_206833	CTXN1	cortexin 1
chr6_+_44302973	0.389		SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr19_-_13074669	0.389		LYL1	lymphoblastic leukemia derived sequence 1
chr2_-_192767494	0.389		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr16_-_4795160	0.388		GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr19_+_495026	0.387	NM_005317	GZMM	granzyme M (lymphocyte met-ase 1)
chr22_-_18484695	0.384		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr7_+_100302885	0.382	NM_003302	TRIP6	thyroid hormone receptor interactor 6
chr5_+_109053628	0.382		MAN2A1	mannosidase, alpha, class 2A, member 1
chr12_+_56290229	0.380	NM_001111270	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr11_+_440408	0.380		PTDSS2	phosphatidylserine synthase 2
chr12_+_130979729	0.378	NM_001002019 NM_025215	PUS1	pseudouridylate synthase 1
chr10_+_11247467	0.376		CELF2	CUGBP, Elav-like family member 2
chr5_+_168996852	0.375		DOCK2	dedicator of cytokinesis 2
chr11_-_45896144	0.374	NM_004813 NM_057174	PEX16	peroxisomal biogenesis factor 16
chr19_-_1125201	0.373
chr16_-_65918126	0.373	NM_001100915	KCTD19	potassium channel tetramerisation domain containing 19
chr10_+_80569464	0.372		ZMIZ1	zinc finger, MIZ-type containing 1
chrX_-_153368098	0.371	NM_014235	UBL4A	ubiquitin-like 4A
chr2_-_74583850	0.371	NM_001009812	LBX2	ladybird homeobox 2
chr1_+_22251706	0.370	NM_001039802 NM_001791 NM_044472	CDC42	cell division cycle 42 (GTP binding protein, 25kDa)
chr10_+_73703682	0.370	NM_019058	DDIT4	DNA-damage-inducible transcript 4
chr5_-_134762764	0.368		H2AFY	H2A histone family, member Y
chr4_+_184257337	0.367	NM_024949	WWC2	WW and C2 domain containing 2
chr5_-_172687798	0.367		STC2	stanniocalcin 2
chr1_+_1233834	0.366	NM_153339	PUSL1	pseudouridylate synthase-like 1
chr19_+_55045754	0.366		PTOV1	prostate tumor overexpressed 1
chr19_-_13074973	0.365	NM_005583	LYL1	lymphoblastic leukemia derived sequence 1
chr11_-_118740069	0.364	NM_171997	USP2	ubiquitin specific peptidase 2
chrX_+_152606945	0.364	NM_001142805 NM_005629	SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr1_+_12149637	0.362	NM_001066	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B
chr3_+_4996096	0.362	NM_003670	BHLHE40	basic helix-loop-helix family, member e40
chr9_-_138772506	0.362	NM_178469	LCN8	lipocalin 8
chr22_+_19601721	0.362		CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr8_-_38127489	0.361	NM_000349	STAR	steroidogenic acute regulatory protein
chr22_-_45037882	0.360	NM_006071	PKDREJ	polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chrX_-_153368130	0.357		UBL4A	ubiquitin-like 4A
chr22_-_20235372	0.357	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr22_-_18484428	0.355		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr19_+_34995290	0.355	NM_057182	CCNE1	cyclin E1
chr6_-_86409283	0.354	NM_001159674	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr22_+_21742727	0.353		GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr1_+_107400789	0.353	NM_018137	PRMT6	protein arginine methyltransferase 6
chr22_+_19601723	0.352		CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr15_+_39008822	0.352	NM_019074	DLL4	delta-like 4 (Drosophila)
chr5_-_176763991	0.351		F12	coagulation factor XII (Hageman factor)
chr8_-_71146022	0.350		PRDM14	PR domain containing 14
chr15_-_38362078	0.350	NM_001190479	LOC100131244	hypothetical protein LOC100131244
chr9_+_138900760	0.349	NM_021138	TRAF2	TNF receptor-associated factor 2
chr10_-_43390014	0.349	NM_001099282 NM_001099283 NM_001099284	ZNF239	zinc finger protein 239
chr3_-_50335113	0.348	NM_003773 NM_033158	HYAL2	hyaluronoglucosaminidase 2
chr22_+_48966394	0.348		TRABD	TraB domain containing
chr3_-_46710137	0.348	NM_001190707 NM_147129	ALS2CL	ALS2 C-terminal like
chr7_-_99555399	0.348	NM_001190415	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr22_+_22703107	0.348	NM_001144931	LOC391322	D-dopachrome tautomerase-like
chr22_+_20068039	0.344	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr20_-_56859352	0.344		GNAS-AS1	GNAS antisense RNA 1 (non-protein coding)
chr6_+_108988797	0.342		FOXO3	forkhead box O3
chr7_-_5534737	0.342		ACTB	actin, beta
chr19_-_4674791	0.342		DPP9	dipeptidyl-peptidase 9
chr9_-_139129015	0.342	NM_013379	DPP7	dipeptidyl-peptidase 7
chr22_+_18484810	0.339	NM_002882	RANBP1	RAN binding protein 1
chr3_+_4996305	0.337		BHLHE40	basic helix-loop-helix family, member e40
chr22_+_17539198	0.336
chr16_-_86460529	0.335	NM_003486	SLC7A5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr17_+_35472566	0.333	NM_001190918 NM_003250 NM_199334	THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chr6_-_86409369	0.333		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.33	6.67e-06	GO:0051252	regulation of RNA metabolic process
1.51	2.21e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.29	2.54e-05	GO:0010468	regulation of gene expression
1.28	5.13e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30	5.71e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.14	6.19e-05	GO:0050794	regulation of cellular process
1.23	7.11e-05	GO:0031323	regulation of cellular metabolic process
1.24	7.57e-05	GO:0060255	regulation of macromolecule metabolic process
1.31	8.21e-05	GO:0006355	regulation of transcription, DNA-dependent
1.13	1.18e-04	GO:0065007	biological regulation
1.28	2.05e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.13	2.19e-04	GO:0050789	regulation of biological process
1.26	2.57e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.22	2.95e-04	GO:0080090	regulation of primary metabolic process
1.25	7.41e-04	GO:0009889	regulation of biosynthetic process
1.25	7.51e-04	GO:0031326	regulation of cellular biosynthetic process
1.19	1.88e-03	GO:0019222	regulation of metabolic process
1.08	2.48e-03	GO:0009987	cellular process
1.55	4.16e-03	GO:0010629	negative regulation of gene expression
1.22	4.71e-03	GO:0006810	transport
1.57	5.54e-03	GO:0051253	negative regulation of RNA metabolic process
1.22	6.15e-03	GO:0051234	establishment of localization
1.57	6.69e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.20	6.71e-03	GO:0051179	localization
1.53	7.88e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51	1.46e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.50	2.05e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.47	3.81e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.45	4.96e-02	GO:0010628	positive regulation of gene expression

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	3.01e-10	GO:0044424	intracellular part
1.10	7.22e-10	GO:0005622	intracellular
1.13	8.52e-10	GO:0043226	organelle
1.13	1.14e-09	GO:0043229	intracellular organelle
1.14	7.39e-09	GO:0043231	intracellular membrane-bounded organelle
1.14	7.85e-09	GO:0043227	membrane-bounded organelle
1.13	1.16e-06	GO:0005737	cytoplasm
1.16	2.27e-05	GO:0005634	nucleus
1.16	2.97e-05	GO:0044422	organelle part
1.16	9.73e-05	GO:0044446	intracellular organelle part
1.14	1.31e-04	GO:0044444	cytoplasmic part
1.04	4.88e-04	GO:0044464	cell part
1.04	5.09e-04	GO:0005623	cell
1.69	1.22e-03	GO:0048471	perinuclear region of cytoplasm
1.44	4.62e-03	GO:0031975	envelope
1.24	5.14e-03	GO:0031090	organelle membrane
1.43	7.67e-03	GO:0031967	organelle envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.51	1.73e-06	GO:0030528	transcription regulator activity
1.51	1.79e-06	GO:0001071	nucleic acid binding transcription factor activity
1.51	1.79e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.13	7.01e-05	GO:0005515	protein binding
1.54	1.33e-04	GO:0043565	sequence-specific DNA binding
1.27	1.38e-04	GO:0003677	DNA binding
1.65	1.63e-02	GO:0016563	transcription activator activity
1.06	4.31e-02	GO:0005488	binding